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Eukaryotic Ribosomes: Assembly

  1. Hendrik A Raué

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0003948

eLS

eLS

How to Cite

Raué, H. A. 2005. Eukaryotic Ribosomes: Assembly. eLS. .

Author Information

  1. Vrije Universiteit, Amsterdam, The Netherlands

Publication History

  1. Published Online: 23 SEP 2005

Abstract

Eukaryotic ribosomes contain one copy of each of four different RNA species and about 80 different proteins. These components are assembled into ribosomal subunits in an ordered manner as the precursor ribosomal RNA is processed into the mature form. Pre-rRNA processing and assembly takes place largely in the nucleolus with later stages occurring in the nucleoplasm and finally the cytoplasm. It requires numerous accessory factors, including a large number of small nucleolar ribonucleoprotein particles (snoRNPs).

Keywords:

  • eukaryote;
  • ribosome;
  • nucleolus;
  • snoRNA