Major Histocompatibility Complex: Human
Published Online: 23 SEP 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Penn, D. J. and Ilmonen, P. 2005. Major Histocompatibility Complex: Human. eLS. .
- Published Online: 23 SEP 2005
The major histocompatibility complex (MHC) is a large genetic region that contains the most polymorphic loci known in humans and other vertebrates. MHC genes are the most intensively studied genes because they influence so many important traits, including resistance to infectious diseases, autoimmunity, compatibility of tissue transplants, spontaneous abortion, odour and mating preferences.
- human leucocyte antigen (HLA);
- tissue rejection;
- genetics and disease resistance;
- host–parasite coevolution;
- mating preferences;
- spontaneous abortion