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Ageing and the Immune System

  1. Richard Aspinall

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0004031



How to Cite

Aspinall, R. 2005. Ageing and the Immune System. eLS. .

Author Information

  1. Imperial College London, London, UK

Publication History

  1. Published Online: 23 SEP 2005


The immune system is our own personal biological warfare machine that protects our body from infections by learning the difference between our own body tissues and the body components of invaders. Unfortunately, like all machines it is subject to normal wear and tear and gradually winds down with age; hence, an understanding of the most common causes of the deterioration in function could lead to an opportunity to reverse these processes and prolong the period of protection that the immune system provides.


  • thymic involution;
  • senescence;
  • lymphocyte;
  • immunotherapy