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GABAA Receptors

  1. F Anne Stephenson

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0004058

eLS

eLS

How to Cite

Stephenson, F. A. 2006. GABAA Receptors. eLS. .

Author Information

  1. University of London, London, UK

Publication History

  1. Published Online: 27 JAN 2006

Abstract

GABAA receptors are fast-acting, ligand-gated anion channels that are the major mediators of inhibitory neurotransmission in the mammalian central nervous system. GABAA receptor activity is regulated by phosphorylation as well as being modulated allosterically by a variety of drugs including the anxiolytic benzodiazepines and barbiturates.

Keywords:

  • GABAA receptors;
  • ligand-gated ion channel superfamily;
  • benzodiazepines;
  • neurotransmitter receptor;
  • barbiturates