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Structural Genomics

  1. John Norvell,
  2. Jiayin Li,
  3. Kirstie Saltsman,
  4. Jeremy Berg

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0004104



How to Cite

Norvell, J., Li, J., Saltsman, K. and Berg, J. 2006. Structural Genomics. eLS. .

Author Information

  1. National Institute of General Medical Sciences, Maryland, USA

Publication History

  1. Published Online: 27 JAN 2006


Structural genomics is a new field that aims at the large-scale determination of thousands of carefully selected protein structures. This endeavour will lead to a broad inventory of the protein structures found in nature, many of which will be of biomedical interest. Recent advances in experimental and computational technology, together with the wealth of protein sequence information provided by genome sequencing efforts, have made this formidable task possible.


  • structure;
  • X-ray crystallography;
  • protein family;
  • protein fold;
  • homology modelling