Standard Article

Identification of Protein–Protein Interactions

  1. Julie C Mitchell

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0004107



How to Cite

Mitchell, J. C. 2006. Identification of Protein–Protein Interactions. eLS. .

Author Information

  1. University of Wisconsin, Madison, Wisconsin, USA

Publication History

  1. Published Online: 27 JAN 2006


Protein–protein interactions are the mechanisms underlying many important biological processes. Prediction of protein–protein interactions is performed using a variety of computational methods that employ both ‘first principles’ biophysical calculations as well as knowledge-based informatics techniques.


  • protein interactions;
  • molecular docking;
  • molecular recognition;
  • binding energy;
  • noncovalent bonds