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Haematopoietic Growth Factors: Therapeutic Uses

  1. Monika Engelhardt1,
  2. Yalin Guo1,
  3. Sebastian Fetscher2,
  4. Roland Mertelsmann1

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0004116



How to Cite

Engelhardt, M., Guo, Y., Fetscher, S. and Mertelsmann, R. 2006. Haematopoietic Growth Factors: Therapeutic Uses. eLS. .

Author Information

  1. 1

    University of Freiburg Medical Center, Freiburg, Germany

  2. 2

    Städtisches Krankenhaus Süd, Lübeck, Germany

Publication History

  1. Published Online: 27 JAN 2006


Haematopoietic growth factors (HGF) belong to the family of cytokines that are glycoprotein products of activated cells. Their main biological function is to influence the intercellular cell communication and thereby cell survival, self-renewal, proliferation, differentiation and activation at all levels of haematopoietic cell development. The clinical application of HGF was one of the main contributions in medicine and has increased the therapeutic options achieved during the last two decades of the twentieth century.


  • growth factors;
  • supportive care;
  • G-CSF;
  • erythropoietin;
  • haematopoietic stem cell transplantation