Xenopus Embryo: β-catenin and Dorsal–Ventral Axis Formation
Published Online: 23 SEP 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Moon, R. T. 2005. Xenopus Embryo: β-catenin and Dorsal–Ventral Axis Formation. eLS. .
- Published Online: 23 SEP 2005
During embryonic development of the amphibian, Xenopus laevis, the dorsal side of the embryo forms approximately opposite the sperm entry point, and the anterior and posterior axes are linked to this through the process of gastrulation. The mechanisms responsible for specification of the dorsal axis include a post-fertilization cortical rotation that promotes a dorsal accumulation of β-catenin, and the activation of a cascade of regulatory genes by the complexes of β-catenin and HMG box transcription factors that start the process of gastrulation.
- gene expression;