Caenorhabditis elegans Vulval Induction
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Sternberg, P. W. 2006. Caenorhabditis elegans Vulval Induction. eLS. .
- Published Online: 27 JAN 2006
Study of Caenorhabditis elegans vulval development has improved our understanding of inductive signalling and pattern formation at the single cell level, and has led to the definition of signalling cascades. Studies of signal transduction during vulval development have led to the discovery of what is considered a universal signalling pathway from growth factor receptor to RAS to MAP kinase to the nucleus, and the discovery of the LIN-12/Notch family of receptors that mediate lateral signalling.
- intercellular signalling;
- signal transduction;
- pattern formation;
- cell lineage