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Botulinum Toxin

  1. James E Keller,
  2. Willie F Vann

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0004218

Book Title

eLS

eLS

Additional Information

How to Cite

Keller, J. E. and Vann, W. F. 2006. Botulinum Toxin. eLS. .

Author Information

  1. Center for Biologics Evaluation and Research, Bethesda, Maryland, USA

Publication History

  1. Published Online: 27 JAN 2006
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Abstract

Botulinum neurotoxin is produced by the bacteria Clostridium botulinum and causes the rare paralytic disease botulism. Purified toxin has gained acceptance to temporarily treat certain human diseases characterized by excessive nerve activity, and also for cosmetic treatment of facial ageing (e.g. BOTOX®).

Keywords:

  • botulism;
  • clostridium botulinum;
  • SNARE protein;
  • zinc metalloprotease;
  • bioterrorism
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