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Chromosomal Bands and Sequence Features

  1. Gerald P Holmquist

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005002



How to Cite

Holmquist, G. P. 2005. Chromosomal Bands and Sequence Features. eLS. .

Author Information

  1. City of Hope, Duarte, California, USA

Publication History

  1. Published Online: 23 SEP 2005


The linear order of DNA is preserved during chromosome condensation. Metaphase chromosome bands are clusters of contiguous replicons of 2–10 Mb that initiate and terminate DNA synthesis in synchrony during a small fraction of S phase.


  • epigenetics;
  • DNA replication;
  • base composition;
  • CpG islands