Genetic Variation: Polymorphisms and Mutations
Published Online: 23 SEP 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Wright, A. F. 2005. Genetic Variation: Polymorphisms and Mutations. eLS. .
- Published Online: 23 SEP 2005
The amount of sequence variation in different regions of the human genome varies by an order of magnitude. Mutations give rise to all variation, but their survival in the genome is influenced by many factors including effects on reproductive fitness, human population history, chromosomal location and recombination rates.
- sequence variation;
- single nucleotide polymorphism;
- population history