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Matrix-associated Regions (MARs) and Scaffold Attachment Regions (SARs)

  1. Sergey V Razin

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005035

eLS

eLS

How to Cite

Razin, S. V. 2005. Matrix-associated Regions (MARs) and Scaffold Attachment Regions (SARs). eLS. .

Author Information

  1. Russian Academy of Sciences, Moscow, Russia

Publication History

  1. Published Online: 23 SEP 2005

Abstract

Matrix-associated regions and scaffold attachment regions are eukaryotic deoxyribonucleic acid sequence elements that can selectively bind isolated nuclear matrix in the presence of a vast excess of competitor prokaryotic DNA. They are thought to participate in chromatin loop anchorage to the nuclear matrix, although this supposition lacks direct experimental proof.

Keywords:

  • nuclear matrix;
  • nuclear scaffold;
  • DNA loop anchorage regions;
  • chromatin domain bordering elements