Standard Article

RNA Processing

  1. Christopher WJ Smith,
  2. ADJ Scadden

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005036

eLS

eLS

How to Cite

Smith, C. W. and Scadden, A. 2005. RNA Processing. eLS. .

Author Information

  1. University of Cambridge, Cambridge, UK

Publication History

  1. Published Online: 23 SEP 2005

Abstract

Eukaryotic RNA transcripts undergo multiple processing reactions before becoming mature functional RNA products. Processing reactions involve base and sugar modifications as well as the removal of noncoding sequences (introns). RNA processing is not only necessary for proper gene expression, but also allows individual genes to produce multiple protein isoforms by alternative splicing and RNA editing.

Keywords:

  • splicing;
  • editing;
  • nucleotide modification;
  • gene expression;
  • ribonucleic acid