Standard Article

SR Proteins

  1. Brenton R Graveley1,
  2. Klemens J Hertel2

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005039



How to Cite

Graveley, B. R. and Hertel, K. J. 2005. SR Proteins. eLS. .

Author Information

  1. 1

    University of Connecticut Health Center, Farmington, Connecticut, USA

  2. 2

    University of California Irvine, Irvine, California, USA

Publication History

  1. Published Online: 23 SEP 2005


Members of the serine/arginine-rich (SR) protein family have several important functions in mRNA biogenesis. SR proteins are essential splicing factors that also participate in the regulation of alternative splicing and the export of mRNAs from the nucleus to the cytoplasm.


  • SR protein;
  • splicing;
  • alternative splicing;
  • RNA-binding protein;
  • mRNA export