Published Online: 23 SEP 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Kaufmann, E. and Knöchel, W. 2005. Forkhead Domains. eLS.
- Published Online: 23 SEP 2005
The forkhead domain or box represents an evolutionarily conserved DNA-binding motif of winged helix structure that has a degree of similarity to the helix–turn–helix motif found in other DNA-binding proteins. Forkhead box (Fox) proteins are involved in a variety of biological processes such as early embryogenesis, organogenesis, tumorigenesis and signal transduction.
- transcription factors;
- gene regulation;
- DNA–protein interaction;
- signal transduction;