Standard Article

Multidomain Proteins

  1. Thomas Traut

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005053



How to Cite

Traut, T. 2005. Multidomain Proteins. eLS. .

Author Information

  1. University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA

Publication History

  1. Published Online: 23 SEP 2005

This is not the most recent version of the article. View current version (15 MAY 2014)


Protein domains that have a necessary function are often used in many different proteins. Protein architecture has evolved to utilize a large set of such domains in forming the thousands of different proteins necessary for any living organism. Simple proteins normally contain only one or a few domains, while larger proteins may have incorporated more than 30 domains needed for the more complex cellular functions.


  • protein structure;
  • domain;
  • module;
  • evolution;
  • protein databases