DNA Polymerases: Eukaryotic
Published Online: 23 SEP 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Hübscher, U. 2005. DNA Polymerases: Eukaryotic. eLS. .
- Published Online: 23 SEP 2005
Deoxyribonucleic acid (DNA) polymerases are enzymes that can use the four bases A, T, G and C to synthesize DNA according to the Watson–Crick base-pair rule (A to T and G to C). They require a template DNA and a nucleic acid (ribonucleic acid or DNA) for initiation of DNA synthesis and use the energy of the four deoxyribonucleoside 5′ triphosphates to incorporate deoxyribonucleoside 5′ monophosphates onto the template DNA.
- DNA polymerases;
- DNA replication;
- DNA repair mechanisms;
- translesion DNA synthesis;
- cell-cycle and checkpoint functions