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RNA Polymerases and the Eukaryotic Transcription Machinery

  1. Nancy A Woychik

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005059

eLS

eLS

How to Cite

Woychik, N. A. 2005. RNA Polymerases and the Eukaryotic Transcription Machinery. eLS. .

Author Information

  1. University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey, USA

Publication History

  1. Published Online: 23 SEP 2005

Abstract

RNA polymerase and its associated proteins play a central role in human gene regulation. This transcription machinery is poised to sense and respond to the multiplicity of cellular signals designed to customize synthesis of both the amount and type of RNA based on the specialized needs of cells comprising human tissues.

Keywords:

  • transcription;
  • RNA polymerase;
  • subunit;
  • Mediator;
  • elongation;
  • chromatin