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Molecular Machines and Human Disorders

  1. Fumio Oosawa

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005168



How to Cite

Oosawa, F. 2005. Molecular Machines and Human Disorders. eLS. .

Author Information

  1. Aichi Institute of Technology, Aichi, Japan

Publication History

  1. Published Online: 23 SEP 2005


Living cells contain various kinds of molecular machine constructed from protein molecules, sometimes with nucleic acid molecules. They work for free energy conversion, information transfer and the performance of specific physical and chemical processes.


  • ATP synthetase;
  • sliding machine;
  • cargo transport;
  • proteasome;
  • chaperonin;
  • syndromes;
  • neuropathy;
  • cardiomyopathy;
  • deafness;
  • myosin family;
  • troponins