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Cell Adhesion Molecules and Human Disorders

  1. Ulrich Müller

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005169

eLS

eLS

How to Cite

Müller, U. 2005. Cell Adhesion Molecules and Human Disorders. eLS. .

Author Information

  1. The Scripps Research Institute, La Jolla, California, USA

Publication History

  1. Published Online: 23 SEP 2005

Abstract

Cell adhesion molecules are cell surface receptors that promote cell–cell and cell–extracellular matrix interactions. Mutations in genes encoding cell adhesion molecules cause inherited disorders affecting many organs such as the skin, kidney and muscle, and the immune and nervous systems.

Keywords:

  • cadherin;
  • dystroglycan;
  • extracellular matrix;
  • Ig-superfamily;
  • integrin