Standard Article

Genetic Isolates and Behavioral Gene Searches

  1. Carlos N Pato1,
  2. Kim M Schindler2,
  3. Michele T Pato1

Published Online: 15 JUL 2006

DOI: 10.1038/npg.els.0005227

eLS

eLS

How to Cite

Pato, C. N., Schindler, K. M. and Pato, M. T. 2006. Genetic Isolates and Behavioral Gene Searches. eLS. .

Author Information

  1. 1

    State University of New York, Syracuse, New York, USA

  2. 2

    State University of New York at Buffalo, Buffalo, New York, USA

Publication History

  1. Published Online: 15 JUL 2006

Abstract

Genetically isolated populations, created via physical isolation, founder effect and ethnic inbreeding, help to create relatively more homogeneous study populations. In the study of disorders of multifactorial and multiple gene effects, use of such populations should allow for enhanced identification of susceptibility genes by limiting genetic heterogeneity.

Keywords:

  • genetic isolates;
  • founder effect;
  • homozygosity;
  • inbreeding;
  • surname analysis