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Epigenetics: Influence on Behavioral Disorders

  1. Arturas Petronis

Published Online: 15 JUL 2006

DOI: 10.1038/npg.els.0005234



How to Cite

Petronis, A. 2006. Epigenetics: Influence on Behavioral Disorders. eLS. .

Author Information

  1. Centre for Addiction and Mental Health, Toronto, Ontario, Canada

Publication History

  1. Published Online: 15 JUL 2006


Epigenetic modifications of the genome are critically important for normal functioning of a cell. In addition to DNA sequence variation, which has been the primary research target in human morbid biology, epigenetic dysregulation of genes may represent a fundamental mechanism of human diseases.


  • epigenetics;
  • neuropsychiatric disorders;
  • Prader–Willi and Angelman syndromes;
  • fragile X mental retardation;
  • Rett syndrome;
  • complex non-Mendelian diseases;
  • schizophrenia;
  • DNA methylation;
  • histone acetylation