Standard Article

FASTA Algorithm

  1. William R Pearson

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005255



How to Cite

Pearson, W. R. 2005. FASTA Algorithm. eLS. .

Author Information

  1. University of Virginia, Charlottesville, Virginia, USA

Publication History

  1. Published Online: 23 SEP 2005

This is not the most recent version of the article. View current version (15 APR 2014)


The FASTA programs search protein and DNA databases for sequences with statistically significant similarity. The programs compare proteins, DNA and short peptides and oligonucleotides, and run on most popular computers.


  • sequence similarity;
  • homology;
  • statistical significance;
  • protein sequence comparison;
  • DNA sequence comparison