Standard Article

Alignment: Statistical Significance

  1. Richard Mott

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005264

eLS

eLS

How to Cite

Mott, R. 2005. Alignment: Statistical Significance. eLS. .

Author Information

  1. University of Oxford, Oxford, UK

Publication History

  1. Published Online: 23 SEP 2005

Abstract

Computation of the probability that an observed alignment between two protein or DNA sequences could have arisen by chance is useful for identifying genuinely related sequences.

Keywords:

  • sequence alignment;
  • statistical significance;
  • homology;
  • DNA;
  • protein sequence