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DNA Recombination

  1. Shunichi Takeda,
  2. Mitsuyoshi Yamazoe

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005283



How to Cite

Takeda, S. and Yamazoe, M. 2005. DNA Recombination. eLS. .

Author Information

  1. Kyoto University, Kyoto, Japan

Publication History

  1. Published Online: 23 SEP 2005


DNA recombination plays an essential role both in generating genetic diversity during lymphocyte development and meiosis and in maintaining genome stability through DNA double-strand break repair. In DNA recombination, two broad classes are commonly recognized: general recombination and site-specific recombination.


  • double-strand break repair;
  • nonhomologous end-joining;
  • homologous recombination;
  • immunoglobulin gene rearrangement