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DNA Repair

  1. Simon Huw Reed,
  2. Raymond Waters

Published Online: 23 SEP 2005

DOI: 10.1038/npg.els.0005284



How to Cite

Reed, S. H. and Waters, R. 2005. DNA Repair. eLS. .

Author Information

  1. University of Wales College of Medicine, Cardiff, UK

Publication History

  1. Published Online: 23 SEP 2005


The primary structure of DNA is subject to constant change caused by chemical and physical factors. If unchecked, these changes would quickly erode the genetic information. DNA repair mechanisms have evolved to remove potentially deleterious damage and maintain the integrity of the genome in all organisms.


  • DNA repair syndromes;
  • nucleotide excision repair;
  • base excision repair;
  • mismatch repair;
  • recombinational repair