Published Online: 23 SEP 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Pomeranz Krummel, D. A. and Nagai, K. 2005. Spliceosome. eLS. .
- Published Online: 23 SEP 2005
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The removal of introns and the splicing together of the protein-coding regions or exons from precursor messenger RNA (pre-mRNA) transcripts is fundamental to the development and maintenance of human cells. The nuclear process of pre-mRNA splicing is a complex phenomenon catalyzed by the ‘spliceosome’, which comprises more than 100 hundred protein and RNA molecules that come on and off during its assembly and activity.
- RNA splicing;
- pre-mRNA transcript;