Published Online: 23 SEP 2005
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Dear, P. H. 2005. HAPPY Mapping. eLS. .
- Published Online: 23 SEP 2005
HAPPY mapping is a versatile in vitro method for making genome maps. Genomic deoxyribonucleic acid (DNA) is broken randomly and diluted to the point where samples contain only a few molecules. If two sequences (‘markers’) are then found together in the same sample, this implies that they are on the same DNA fragment and therefore adjacent in the genome.
- genome mapping;
- single-molecule analysis;
- linkage analysis;
- polymerase chain reaction