Genetic Maps: Integration
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Collins, A. 2006. Genetic Maps: Integration. eLS. .
- Published Online: 27 JAN 2006
Genetic maps describe the order of polymorphisms along a chromosome; however, unlike physical maps, the map distances are related to recombination. The level of recombination varies with position along the chromosome and between the sexes. It is important to integrate genetic and physical or sequence-based maps to identify regions of elevated or reduced recombination. The presence of recombination hot and cold spots has a bearing on efforts to map disease genes and for the understanding of the biological properties of chromosome location.
- linkage mapping;
- map integration