Sample Size Requirements
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Knapp, M. 2006. Sample Size Requirements. eLS. .
- Published Online: 27 JAN 2006
Sample size requirements in the context of linkage analysis between a trait and genetic markers refer to the calculation of the sample size required for a linkage study to guarantee a certain power of the study against an assumed inheritance model. The power against an assumed inheritance model is the probability of correctly declaring a linkage when in fact the assumed inheritance model is true and the trait and marker loci are linked.
- inheritance model;
- parametric linkage analysis;
- affected sibling pair test;
- transmission/disequilibrium test