Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Hall, J. G. 2006. Mosaicism. eLS. .
- Published Online: 27 JAN 2006
Mosaicism refers to the presence of genetically different cells in a multicellular organism that have been derived from a single fertilized egg. The genetic change can take many forms and occur through many mechanisms. The clinical manifestations of mosaicism may be reflected in patchy or streaky pigment, overgrowth or undergrowth, and asymmetric growth or anomalies. When considering mosaicism, it is important to study other tissues in addition to blood.
- germ-line mosaicism;
- somatic cell mosaicism;
- clinical abnormalities