Standard Article


  1. Judith G Hall

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005478



How to Cite

Hall, J. G. 2006. Mosaicism. eLS. .

Author Information

  1. University of British Columbia, Vancouver, Canada

Publication History

  1. Published Online: 27 JAN 2006


Mosaicism refers to the presence of genetically different cells in a multicellular organism that have been derived from a single fertilized egg. The genetic change can take many forms and occur through many mechanisms. The clinical manifestations of mosaicism may be reflected in patchy or streaky pigment, overgrowth or undergrowth, and asymmetric growth or anomalies. When considering mosaicism, it is important to study other tissues in addition to blood.


  • mosaicism;
  • chimera;
  • germ-line mosaicism;
  • somatic cell mosaicism;
  • mutation;
  • clinical abnormalities