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Posttranslational Modification and Human Disorders

  1. G Brian Wisdom

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005498



How to Cite

Wisdom, G. B. 2006. Posttranslational Modification and Human Disorders. eLS. .

Author Information

  1. The Queen's University, Belfast, UK

Publication History

  1. Published Online: 27 JAN 2006


Most proteins undergo modification involving specific cleavage of the polypeptide backbone and/or changes to the side chains. Some of these modifications result in disease or disorder; others may be used diagnostically.


  • posttranslational;
  • processing;
  • amyloid;
  • glycosylation;
  • toxins