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Kidney: Hereditary Disorders

  1. Ernie L Esquivel,
  2. Stefan Somlo

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005519

eLS

eLS

How to Cite

Esquivel, E. L. and Somlo, S. 2006. Kidney: Hereditary Disorders. eLS. .

Author Information

  1. Yale University School of Medicine, New Haven, Connecticut, USA

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Hereditary disorders of the kidney consist of a heterogeneous group of diseases characterized by abnormalities in the ability of the kidneys to filter waste products and/or maintain acid–base and fluid homeostasis. Elucidation of the underlying genetic lesions has enhanced our basic understanding of renal physiology, as well as of normal kidney development and cellular differentiation.

Keywords:

  • kidney diseases;
  • kidney development;
  • ion transport;
  • hypertension;
  • acid–base balance;
  • electrolytes