Fusion Proteins and Diseases
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Saha, V. and Jones, L. K. 2006. Fusion Proteins and Diseases. eLS. .
- Published Online: 27 JAN 2006
Fusion proteins occur as a result of chromosomal translocations in cancerous cells. The proteins targeted are either transcription factors or tyrosine kinases. The fusion proteins are associated with developmental malignancies and thyroid carcinomas.
- chromosomal translocations;
- transcription factors;
- tyrosine kinase;
- thyroid carcinoma;
- cell-cycle signaling pathways