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DNA Chips and Microarrays

  1. Torben F Orntoft,
  2. Mogens Kruhøffer

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005675

eLS

eLS

How to Cite

Orntoft, T. F. and Kruhøffer, M. 2006. DNA Chips and Microarrays. eLS. .

Author Information

  1. Aarhus University Hospital, skejby, Denmark

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Parallel analyses of thousands of molecules based on hybridization to nucleotides are carried out on microarrays. The large amount of data generated from scanning such arrays needs bioinformatic handling in the form of noise filtering, calibration and normalization to be ready for experimental comparison with other arrays. This may provide insight into regulatory pathways and lead to reclassification of diseases.

Keywords:

  • DNA chips;
  • microarrays;
  • gene expression;
  • SNP arrays;
  • arrays