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Fluorescence In Situ Hybridization (FISH) Techniques

  1. Michael R Speicher

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005779



How to Cite

Speicher, M. R. 2006. Fluorescence In Situ Hybridization (FISH) Techniques. eLS. .

Author Information

  1. Technical University Munich and GSF-Neuherberg, Munich, Germany

Publication History

  1. Published Online: 27 JAN 2006


Fluorescence in situ hybridization allows the visualization and analysis of chromosomal regions on metaphase spreads and in interphase nuclei. The multitude of different FISH technologies and applications range from its use in diagnostics to areas in basic research.


  • chromosome analysis;
  • interphase cytogenetics;
  • multicolour-FISH;
  • high-resolution mapping