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Chromosome 22

  1. Beverly S Emanuel,
  2. Tamim H Shaikh

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005831



How to Cite

Emanuel, B. S. and Shaikh, T. H. 2006. Chromosome 22. eLS. .

Author Information

  1. The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA

Publication History

  1. Published Online: 27 JAN 2006


Human chromosome 22 is the second smallest of the autosomes and contains ∼1.7% of the genetic material in the genome. It is relatively gene-rich and contains clusters of rRNA and immunoglobulin lambda light chain genes.


  • chromosome 22;
  • sequencing;
  • DiGeorge syndrome;
  • velocardiofacial syndrome;
  • recurrent translocations;
  • low copy repeats