Major Histocompatibility Complex (MHC) Genes
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Kulski, J. K. and Inoko, H. 2006. Major Histocompatibility Complex (MHC) Genes. eLS. .
- Published Online: 27 JAN 2006
MHC genes are located within the human major histocompatibility complex (MHC) and code for different members of the class I and the class II human leukocyte antigen (HLA) families. The HLA class I and class II molecules are polymorphic cell membrane-bound glycoproteins and, as part of the immunosurveillance system, they regulate the immune response by presenting fragmented proteins (peptides) to circulating cytotoxic and helper T lymphocytes respectively.
- class I;
- class II;