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Chromosome X

  1. Brunella Franco

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005924



How to Cite

Franco, B. 2006. Chromosome X. eLS. .

Author Information

  1. Telethon Institute of Genetics and Medicine, Naples, Italy

Publication History

  1. Published Online: 27 JAN 2006


The human X chromosome is a submetacentric chromosome that contains ∼5% of the genetic material in the genome. It is characterized by two X–Y homologous (pseudoautosomal) regions that are necessary for normal meiosis. The chromosome is relatively gene-rich and most of these are subject to X-inactivation.


  • chromosome X;
  • sequencing;
  • X inactivation;
  • X-linked diseases, chromosomal abnormalities