Standard Article

Systems Biology: Genomics Aspects

  1. Andrzej K Konopka

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005928

eLS

eLS

How to Cite

Konopka, A. K. 2006. Systems Biology: Genomics Aspects. eLS. .

Author Information

  1. BioLingua Research Inc., Gaithersburg, Maryland, USA

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Systems biology is concerned with functionally complex systems (such as an organism, immune system or ecosystem) that can be approximately described by several complementary models but cannot be adequately represented by a single model. It addresses foundational issues of ‘entire’ biology (such as system modeling, fractionation, integration and emergence) but it is also devoted to specific techniques for data integration and interpretation. This brings systems biology right in the middle of the old controversy between reductionism and holism.

Keywords:

  • system;
  • function;
  • complexity;
  • causality;
  • modeling;
  • reductionism;
  • holism;
  • emergence;
  • metabolism;
  • networks;
  • automata