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Venous Thrombosis: Genetics

  1. Pieter H Reitsma

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005932



How to Cite

Reitsma, P. H. 2006. Venous Thrombosis: Genetics. eLS. .

Author Information

  1. Laboratory for Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Publication History

  1. Published Online: 27 JAN 2006


The genetics of venous thrombosis provides a well worked out example of a multifactorial disease. Several genetic risk factors have been characterized in considerable detail, and evaluation of these risk factors is helpful in assessing individual risk profiles.


  • venous thrombosis;
  • antithrombin;
  • heparin cofactor II;
  • protein C;
  • protein S;
  • thrombomodulin;
  • endothelial-cell protein C receptor;
  • tissue factor pathway inhibitor;
  • factor V;
  • prothrombin;
  • factor XIII;
  • tissue factor