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Severe Combined Immune Deficiency (SCID): Genetics

  1. A Fischer

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005941

eLS

eLS

How to Cite

Fischer, A. 2006. Severe Combined Immune Deficiency (SCID): Genetics. eLS. .

Author Information

  1. Hôpital Necker, Paris, France

Publication History

  1. Published Online: 27 JAN 2006

This is not the most recent version of the article. View current version (15 NOV 2011)

Abstract

Severe combined immunodeficiency consists of an array of genetically determined blocks in T lymphocyte development. Characterization of genetic defects contributes to a better understanding of lymphocyte differentiation pathways.

Keywords:

  • Severe combined immunodeficiencies;
  • hematopoietic stem cells;
  • T lymphocytes;
  • B lymphocytes;
  • NK lymphocytes;
  • lymphocyte differentiation