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Microarrays and Single Nucleotide Polymorphism (SNP) Genotyping

  1. Andres Metspalu

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005948

eLS

eLS

How to Cite

Metspalu, A. 2006. Microarrays and Single Nucleotide Polymorphism (SNP) Genotyping. eLS. .

Author Information

  1. University of Tartu, Tartu, Estonia

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Microarrays are used for genotyping projects that cover one gene, many candidate genes or whole sets of chromosomes in a genome, and are capable of analyzing thousands of Single nucleotide polymorphisms (SNPs) in parallel. SNP-based linkage disequilibrium maps and haplotypes, either measured directly or calculated from the SNP genotyping data, will be in use in the near future for studies of genome-wide genetic association in common diseases.

Keywords:

  • microarrays;
  • APEX;
  • genotyping;
  • linkage disequilibrium;
  • haplotypes