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Microarrays in Drug Discovery and Development

  1. Christine Debouck1,
  2. Allen D Roses2

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005951



How to Cite

Debouck, C. and Roses, A. D. 2006. Microarrays in Drug Discovery and Development. eLS. .

Author Information

  1. 1

    GlaxoSmithKline, King of Prussia, Pennsylvania, USA

  2. 2

    GlaxoSmithKline, Research Triangle Park, North Carolina, USA

Publication History

  1. Published Online: 27 JAN 2006


Microarrays are used to analyze the expression of thousands of genes in parallel, allowing studies of tissue distribution patterns associated with normal physiology and diseases and with the effects of compounds, in terms of safety and efficacy in model organisms and in humans.


  • expression profiling;
  • gene chips;
  • target validation;
  • toxicogenomics;
  • pharmacogenomics