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Microarrays: Use in Gene Identification

  1. David R Rank1,
  2. David K Hanzel1,
  3. David Jenkins1,
  4. Russell S Thomas1,
  5. Mark Shannon1,
  6. Jinjiao Guo1,
  7. Amy Corrigan1,
  8. Jian Zhang1,
  9. Yizhong Gu1,
  10. Wensheng Chen1,
  11. Yonggang Ji1,
  12. Tianhua Hu1,
  13. David L Barker2,
  14. Sharron G Penn1

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005952

eLS

eLS

How to Cite

Rank, D. R., Hanzel, D. K., Jenkins, D., Thomas, R. S., Shannon, M., Guo, J., Corrigan, A., Zhang, J., Gu, Y., Chen, W., Ji, Y., Hu, T., Barker, D. L. and Penn, S. G. 2006. Microarrays: Use in Gene Identification. eLS. .

Author Information

  1. 1

    Aeomica Inc., Sunnyvale, California, USA

  2. 2

    Illumina Inc., San Diego, California, USA

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Gene prediction by computer algorithms and approaches based on comparative genomics identifies the presence of potential genes in a genomic sequence. By placing these predicted genes onto microarrays and searching for interactions with complementary DNA from different types of tissue or cell, novel genes are discovered.

Keywords:

  • gene prediction;
  • comparative genomics;
  • chromosome 22;
  • myosin;
  • open reading frame