Promoter Haplotypes and Gene Expression
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Joosten, P. H. 2006. Promoter Haplotypes and Gene Expression. eLS. .
- Published Online: 27 JAN 2006
There is an estimated 0.1% difference between any two human genomes. The differences occur predominantly outside protein-coding regions and result in, for example, different promoter haplotypes. The generation of a high-resolution human genomic sequence will allow us to investigate the role of genetic variance in common diseases, which tend to be multifactorial with a non-Mendelian inheritance.