Standard Article

RNA-binding Proteins: Regulation of mRNA Splicing, Export and Decay

  1. Jayanthi P Gudikote,
  2. Miles F Wilkinson

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005982

eLS

eLS

How to Cite

Gudikote, J. P. and Wilkinson, M. F. 2006. RNA-binding Proteins: Regulation of mRNA Splicing, Export and Decay. eLS. .

Author Information

  1. University of Texas MD Anderson Cancer Center, Houston, Texas, USA

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Mammalian messenger ribonucleic acid (mRNA)-binding proteins regulate gene expression at several steps including pre-mRNA processing, nucleocytoplasmic export and degradation.

Keywords:

  • pre-mRNA processing;
  • mRNA transport;
  • mRNA stability;
  • RNA splicing;
  • RNA-binding proteins;
  • nonsense-mediated mRNA decay;
  • exon-junction complex