Standard Article

Histone Acetylation: Long-range Patterns in the Genome

  1. Emery H Bresnick,
  2. Hogune Im,
  3. Kirby D Johnson

Published Online: 27 JAN 2006

DOI: 10.1038/npg.els.0005987

eLS

eLS

How to Cite

Bresnick, E. H., Im, H. and Johnson, K. D. 2006. Histone Acetylation: Long-range Patterns in the Genome. eLS. .

Author Information

  1. University of Wisconsin Medical School, Madison, Wisconsin, USA

Publication History

  1. Published Online: 27 JAN 2006

Abstract

Modification of core histones by acetylation establishes a chromatin environment permissive for gene expression. Complex patterns of acetylation spanning many kilobases have been identified at certain loci. However, little is known about the regulation and functional consequences of these broad domains of acetylation.

Keywords:

  • histone;
  • acetylation;
  • chromatin;
  • chromosome;
  • epigenetics;
  • transcription