Gene Targeting by Homologous Recombination
Published Online: 27 JAN 2006
Copyright © 2001 John Wiley & Sons, Ltd. All rights reserved.
How to Cite
Wilson, J. H. and Vasquez, K. M. 2006. Gene Targeting by Homologous Recombination. eLS. .
- Published Online: 27 JAN 2006
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Homologous recombination involves the exchange of DNA molecules in regions of homology by a crossover event. Homologous recombination provides a mechanism for targeting defined modifications into genes of interest.
- homologous recombination;
- gene targeting;
- mouse disease models;
- genome modification;
- triplex technology